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Cross-flow filtration : ウィキペディア英語版
Cross-flow filtration

In chemical engineering, biochemical engineering and protein purification, crossflow filtration (also known as tangential flow filtration〔(Millipore Technical Library: Protein Concentration and Diafiltration by Tangential Flow Filtration )〕) is a type of filtration (a particular unit operation). Crossflow filtration is different from dead-end filtration in which the feed is passed through a membrane or bed, the solids being trapped in the filter and the filtrate being released at the other end. Cross-flow filtration gets its name because the majority of the feed flow travels tangentially ''across'' the surface of the filter, rather than into the filter.〔 The principal advantage of this is that the filter cake (which can blind the filter) is substantially washed away during the filtration process, increasing the length of time that a filter unit can be operational. It can be a continuous process, unlike batch-wise dead-end filtration.
This type of filtration is typically selected for feeds containing a high proportion of small particle size solids (where the permeate is of most value) because solid material can quickly block (blind) the filter surface with dead-end filtration. Industrial examples of this include the extraction of soluble antibiotics from fermentation liquors.
==Operation==

In crossflow filtration, the feed is passed across the filter membrane (tangentially) at positive pressure relative to the permeate side. A proportion of the material which is smaller than the membrane pore size passes through the membrane as permeate or filtrate; everything else is retained on the feed side of the membrane as retentate.
With crossflow filtration the tangential motion of the bulk of the fluid across the membrane causes trapped particles on the filter surface to be rubbed off. This means that a crossflow filter can operate continuously at relatively high solids loads without blinding.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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